914300-73-5

Basic information

• Product Name: (Z)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-trifluoromethanesulfonyloxy-pent-2-enoic acid methyl ester
• Synonyms: (Z)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-trifluoromethanesulfonyloxy-pent-2-enoic acid methyl ester
• CAS NO: 914300-73-5
• Molecular Weight: 412.384
• Mol File: 914300-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-trifluoromethanesulfonyloxy-pent-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-trifluoromethanesulfonyloxy-pent-2-enoic acid methyl ester(914300-73-5)
• EPA Substance Registry System: (Z)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-trifluoromethanesulfonyloxy-pent-2-enoic acid methyl ester(914300-73-5)

Safety Data

• Hazardous Substances Data: 914300-73-5(Hazardous Substances Data)

Upstream product

• 212051-35-9 (R)-methyl 3-((4-methoxybenzyl)oxy)-2-methylpropanoate 
• 914300-71-3 (E)-(S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-triethylsilanyloxy-pent-2-enoic acid methyl ester 
• 914300-72-4 (S)-5-(4-Methoxy-benzyloxy)-4-methyl-2-oxo-pentanoic acid methyl ester 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 

Downstream Products

• 117582-92-0 iejimalide B 
• 1060673-70-2 C₂₁H₂₄O₄ 
• 914300-74-6 (E)-(S)-5-(4-Methoxy-benzyloxy)-2,4-dimethyl-pent-2-enoic acid methyl ester 

Relevant articles and documents

Total synthesis of iejimalide B

(Chemical Equation Presented) Metathesis to the rescue: Although counterintuitive at first sight, application of ring-closing metathesis (RCM) to a cyclization precursor containing 10 double bonds has led to the selective and high-yielding formation of the macrocyclic core of iejimalide B, a potent cytotoxic agent of marine origin. In contrast, a macrolactonization approach failed to afford this intricate target.