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2-Amino-5-chlorothiazole-4-carboxylic acid methyl ester, with the molecular formula C6H6ClN3O2S, is a chemical compound that serves as a crucial intermediate in the synthesis of pharmaceuticals and agrochemicals. Known for its antimicrobial and antifungal properties, this versatile chemical is valued for its increased stability and solubility in various solvents due to its methyl ester form, making it a significant component in both the pharmaceutical and agricultural industries.

914348-76-8

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914348-76-8 Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-5-chlorothiazole-4-carboxylic acid methyl ester is used as an intermediate in the synthesis of various medications for its antimicrobial and antifungal properties. It contributes to the development of drugs that combat a range of microbial infections, enhancing the effectiveness of treatment options.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-5-chlorothiazole-4-carboxylic acid methyl ester is utilized as an intermediate in the production of agricultural products with antimicrobial and antifungal properties. This application helps in creating more effective pesticides and fungicides, thereby improving crop yields and protecting plants from diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 914348-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,3,4 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 914348-76:
(8*9)+(7*1)+(6*4)+(5*3)+(4*4)+(3*8)+(2*7)+(1*6)=178
178 % 10 = 8
So 914348-76-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2O2S/c1-10-4(9)2-3(6)11-5(7)8-2/h1H3,(H2,7,8)

914348-76-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-amino-5-chloro-1,3-thiazole-4-carboxylate

1.2 Other means of identification

Product number -
Other names 2-Amino-5-chlorothiazole-4-carboxylic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:914348-76-8 SDS

914348-76-8Downstream Products

914348-76-8Relevant academic research and scientific papers

BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS

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Page/Page column 200; 387-388, (2021/04/17)

Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Such compounds are represented by Formula I as follows: Formula I wherein R1, R2, R3, and Q are defined herein.

2-(1H-INDOLE-3-CARBONYL)-THIAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS

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Paragraph 00162; 00300, (2021/06/26)

2-(1H-lndole-3-carbonyl)-thiazole-4-carboxamide derivatives and the corresponding imidazole, oxazole and thiophene derivatives and related compounds as aryl hydrocarbon receptor (AHR) agonists for the treatment of angiogenesis implicated disorders, such as e.g. retinopathy, psoriasis, rheumatoid arthritis, obesity and cancer, or inflammatory disorders. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. pages 27 to 32 and 59 to 219; examples 1 to 8; compounds 1-1 to 1-97; tables 1-a, 2 and 3).

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