914360-25-1

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 503004-85-1 (2S,4aS,7R,8aR)-[4,4,7-trimethyl-3-(3-methylbut-2-enyl)octahydrobenzo[e][1,3]oxazin-2-yl]methanol 

Downstream Products

• 792886-64-7 (2R)-2-isopropyl-morpholine 
• 914360-12-6 (2R)-2-isopropyl-4-(8-mentholyl)-morpholine 

Relevant academic research and scientific papers

7-endo selenocyclization reactions on chiral 3-prenyl and 3-cinnamyl-2-hydroxymethylperhydro-1,3-benzoxazine derivatives. A way to enantiopure 1,4-oxazepanes

Enantiopure 1,4-oxazepane derivatives have been prepared by selenocyclofunctionalization of chiral 3-prenyl- and 3-cinnamyl-2-hydroxymethyl-substituted perhydro-1,3-benzoxazine derivatives. The 7-endo-cyclization occurs in high yields and diastereoselecti

Diastereoselective synthesis of enantiopure morphelines by electrophilic selenium-induced 6-exo cyclizations on chiral 3-allyl-2-hydroxymethylperhydro-1, 3-benzoxazine derivatives

Enantiopure morpholine derivatives have been prepared by selenocyclofunctionalization of chiral 3-allyl-2-hydroxymethyl-substituted perhydro-1,3-benzoxazine derivatives. The cyclization occurs in high yields and diastereoselection, although the temperature of the reaction and the structure of the substituent at C-2 and the substitution pattern of the double bond can modify the regio- and stereochemistry of the final products.