914397-12-9

Basic information

• Product Name: 6-Bromo-7-methoxy-quinazolin-2-ylamine
• Synonyms: 6-Bromo-7-methoxy-quinazolin-2-ylamine;6-bromo-7-methoxyquinazolin-2-amine
• CAS NO: 914397-12-9
• Molecular Formula: C₉H₈BrN₃O
• Molecular Weight: 254.08332
• Mol File: 914397-12-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Bromo-7-methoxy-quinazolin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-7-methoxy-quinazolin-2-ylamine(914397-12-9)
• EPA Substance Registry System: 6-Bromo-7-methoxy-quinazolin-2-ylamine(914397-12-9)

Safety Data

• Hazardous Substances Data: 914397-12-9(Hazardous Substances Data)

Upstream product

• 593-85-1 guanidine carbonate 
• 1036756-11-2 2-amino-5-bromo-4-methoxybenzaldehyde 
• 331-64-6 2-fluoro-4-methoxy-benzaldehyde 
• 473417-48-0 5-bromo-2-fluoro-4-methoxybenzaldehyde 
• 593-85-1 diguanidine carbonate 

Downstream Products

• 1425504-20-6 (R)-tert-butyl 1-(4-(7-methoxy-6-(pyridin-4-yl)quinazolin-2ylamino)phenyl)ethylcarbamate 
• 1191932-26-9 3-(2-Amino-8-bromo-7-methoxyquinazolin-6-yl)-4-methyl benzoic acid 
• 1191932-18-9 2-amino-8-bromo-7-methoxy-6-[2-methyl-5-((3-trifluoromethyl)benzamido)phenyl]quinazoline 
• 1191932-55-4 2-amino-8-bromo-7-methoxy-6-[2-methyl-5-N-(4-trifluoromethylpyridin-2-yl)carbamoylphenyl]quinazoline 
• 1191929-32-4 2-amino-7-methoxy-6-[2-methyl-5-(3-trifluoromethylbenzamide)phenyl]-8-(2-pyridyl)quinazoline 
• 1191929-31-3 2-amino-7-methoxy-6-[2-methyl-5-(3-trifluoromethylbenzamide)phenyl]-8-phenylquinazoline 
• 1191929-34-6 2-amino-7-hydroxy-6-[2-methyl-5-(3-trifluoromethylbenzamide)phenyl]-8-(2-pyridyl)quinazoline 
• 1191932-28-1 2-amino-8-bromo-6-(5-N-{2-[N-(3-dimethylaminopropyl)-N-methylamino]-5-trifluoromethylphenyl}carbamoyl-2-methylphenyl)-7-methoxyquinazoline 
• 1191932-43-0 2-amino-8-bromo-7-methoxy-6-[2-methyl-5-N-(2-piperidino-5-trifluoromethylphenyl)carbamoylphenyl]quinazoline 
• 1191932-17-8 2-amino-7-methoxy-6-[2-methyl-5-((3-trifluoromethyl)benzamido)phenyl]quinazoline 
• 1191932-25-8 3-(2-Amino-7-methoxyquinazolin-6-yl)-4-methyl benzoic acid 

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2-AMINOQUINAZOLINE DERIVATIVE

A 2-aminoquinazoline derivative represented by formula (I) {wherein R1 represents a hydrogen atom, or the like, R2 represents a hydrogen atom, R3 represents formula (II) [wherein A1 represents formula (III), or the like, R8 represents lower alkyl, or the like, and R9 represents optionally substituted aryl, or the like], R4 represents hydroxy, or the like, and R5 represents optionally substituted aryl, or the like}, or a pharmaceutically acceptable salt thereof is provided.

2-AMINOQUINAZOLINE DERIVATIVES

2-Aminoquinazoline derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 and R2 are each independently hydrogen, substituted or unsubstituted lower alkyl, or the like; X is a bond or CR7aR7b (wherein R7a and R7b are each independently hydrogen or the like); when X is a bond, R3 is substituted or unsubstituted aryl or a substituted or unsubstituted aromatic heterocyclic group, while when X is CR7aR7b, R3 is substituted or unsubstituted lower alkoxy, substituted or unsubstituted aryl, or the like; R4 is hydrogen, hydroxy, substituted or unsubstituted lower alkoxy, or the like; and R5 is hydrogen, substituted or unsubstituted aryl, or the like.