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914458-39-2

(5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)methanone, commonly referred to as AM-2201, is a synthetic cannabinoid compound that engages with the endocannabinoid system within the brain. It functions as a potent agonist of the CB1 receptor, eliciting effects akin to those of THC, the principal psychoactive constituent in cannabis. (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)methanone is recognized for its ability to induce euphoric and psychoactive responses, and while it is often utilized for recreational purposes, it also holds promise for therapeutic uses in managing chronic pain, anxiety, and other medical conditions.

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  • (5-(4-FLUOROPHENYL)-1-PENTYL-1H-PYRROL-3-YL)(NAPHTHALEN-1-YL)METHANONE

    Cas No: 914458-39-2

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  • 914458-39-2 Structure

  • Basic information

    1. Product Name: (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)Methanone
    2. Synonyms: (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)Methanone
    3. CAS NO:914458-39-2
    4. Molecular Formula: C26H24FNO
    5. Molecular Weight: 385
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 914458-39-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)Methanone(CAS DataBase Reference)
    10. NIST Chemistry Reference: (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)Methanone(914458-39-2)
    11. EPA Substance Registry System: (5-(4-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)Methanone(914458-39-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 914458-39-2(Hazardous Substances Data)

914458-39-2 Usage

Uses

Used in Pharmaceutical Industry:
AM-2201 is used as a research chemical for the development of new treatments targeting the endocannabinoid system. Its agonistic action on the CB1 receptor makes it a candidate for potential therapeutic applications in the management of chronic pain and anxiety disorders, given its ability to modulate the brain's response to these conditions.
Used in Neurological Research:
In the field of neuroscience, AM-2201 serves as a valuable tool for studying the endocannabinoid system's role in various physiological and pathological processes. Its interaction with the CB1 receptor aids researchers in understanding the mechanisms underlying the system's influence on mood, appetite, and memory, among other functions.
Used in Toxicological Studies:
AM-2201 is also utilized in toxicological research to investigate the safety and potential risks associated with synthetic cannabinoids. This research is crucial for informing regulations and understanding the compound's impact on human health, especially in the context of recreational use and abuse.

Check Digit Verification of cas no

The CAS Registry Mumber 914458-39-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,4,5 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 914458-39:
(8*9)+(7*1)+(6*4)+(5*4)+(4*5)+(3*8)+(2*3)+(1*9)=182
182 % 10 = 2
So 914458-39-2 is a valid CAS Registry Number.

914458-39-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-(4-Fluorophenyl)-1-pentyl-1H-pyrrol-3-yl)(naphthalen-1-yl)methanone

1.2 Other means of identification

Product number -
Other names [5-(4-fluorophenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:914458-39-2 SDS

914458-39-2Downstream Products

914458-39-2Relevant articles and documents

1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors

Huffman, John W.,Padgett, Lea W.,Isherwood, Matthew L.,Wiley, Jenny L.,Martin, Billy R.

, p. 5432 - 5435 (2007/10/03)

Two series of 1-alkyl-2-aryl-4-(1-naphthoyl)pyrroles were synthesized and their affinities for the cannabinoid CB1 and CB2 receptors were determined. In the 2-phenyl series (5) the N-alkyl group was varied from n-propyl to n-heptyl. A second series of 23 1-pentyl-2-aryl-4-(1-naphthoyl)-pyrroles (6) was also prepared. Several compounds in both series have CB1 receptor affinities in the 6-30 nM range. The high affinities of these pyrrole derivatives relative to JWH-030 (1, R = C5H11) support the hypothesis that these pyrroles interact with the CB1 receptor primarily by aromatic stacking.

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