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Valsartan Impurity 1, also known as N-((2''-(1H-Tetrazol-5-yl)-[1,1''-biphenyl]-4-yl)methyl)pentanamide, is an impurity found in Valsartan (V095750), which is an antihypertensive medication and a nonpeptide angiotensin II AT1-receptor antagonist. This impurity is a chemical byproduct that may be present during the synthesis or manufacturing process of Valsartan.

914465-68-2

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914465-68-2 Usage

Uses

Used in Pharmaceutical Industry:
Valsartan Impurity 1 is used as a reference material for quality control and analytical testing in the pharmaceutical industry. It helps ensure the purity and safety of Valsartan, the active pharmaceutical ingredient, by providing a benchmark for detecting and quantifying impurities during the manufacturing process.
Additionally, understanding the properties and effects of Valsartan Impurity 1 can contribute to the development of improved synthesis methods and purification techniques, ultimately enhancing the overall quality and efficacy of Valsartan as an antihypertensive medication.

Check Digit Verification of cas no

The CAS Registry Mumber 914465-68-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,4,6 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 914465-68:
(8*9)+(7*1)+(6*4)+(5*4)+(4*6)+(3*5)+(2*6)+(1*8)=182
182 % 10 = 2
So 914465-68-2 is a valid CAS Registry Number.

914465-68-2Downstream Products

914465-68-2Relevant academic research and scientific papers

Synthesis and characterization of Irbesartan impurities

Satyanarayana,Anjaneyulu,Veerasomaiah,Pratap Reddy

, p. 223 - 228 (2007)

In the course of synthesis of an antihypertensive drug, Irbesartan, five process related potential impurities were detected by using high performance liquid chromatography. They were synthesized and characterized by NMR, Mass, and IR. Synthesis and charac

Valsartan impurities and synthesis method thereof

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Paragraph 0020-0033, (2018/12/02)

The invention discloses valsartan impurities and a synthesis method thereof. The method comprises the steps of enabling valsartan to be subjected to a reaction at a high temperature in a solvent by using strong alkali or strong acid, then adding acid or a

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