914480-89-0Relevant academic research and scientific papers
Efficient synthesis of 1-(5′-acylamino-1′,3′,4′- thiadiazol-2′-yl)-4-acyl-thiosemicarbazides
Li, Zheng,Yang, Jing-Ya,Wang, Xi-Cun
, p. 2355 - 2362 (2007/10/03)
Acyl chlorides reacted with ammonium thiocyanate and carbonic dihydrazide under phase-transfer catalysis to first afford 2,2′- bis(acylaminothiocarbonyl)-carbonic dihydrazides, which further cyclized in the presence of glacial acetic acid to efficiently give 1-(5′-acylamino- 1′,3′,4′-thiadiazol-2′-yl)-4-acyl-thiosemicarbazides in high yield. Copyright Taylor & Francis Group, LLC.
