914602-68-9Relevant academic research and scientific papers
Peptidyl-urea based inhibitors of soluble epoxide hydrolases
Morisseau, Christophe,Newman, John W.,Tsai, Hsing-Ju,Baecker, Preston A.,Hammock, Bruce D.
, p. 5439 - 5444 (2006)
We prepared a series of amino acid derived cyclohexyl and adamantyl ureas and tested them as inhibitors of the human soluble epoxide hydrolase, and obtained very potent compounds (KI = 15 nM) that are >10-fold more soluble than previously descr
