914616-19-6

Upstream product

• 1166871-17-5 C₂₄H₃₇NO₃ 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 

Downstream Products

• 1166871-18-6 (4S,5R)-1-(2-(methoxymethoxy)allyl)-4-((R)-1-(2,4,6-triisopropylphenyl)ethoxy)-5-((S)-1-(triisopropylsilyloxy)allyl)pyrrolidin-2-one 
• 107244-34-8 6-epi-castanospermine 
• 914616-15-2 (3aR,8S,8aR,9R,9aR)-2,2-dimethyl-8-((R)-1-(2,4,6-triisopropylphenyl)ethoxy)-9-(triiso-propylsilyloxy)-hexahydro-[1,3]dioxolo[4,5-f]indolizin-6(7H)-one 
• 914616-16-3 (3aR,8S,8aR,9R,9aR)-2,2-dimethyl-8-((R)-1-(2,4,6-triisopropylphenyl)ethoxy)-9-(triiso-propylsilyloxy)-octahydro-[1,3]dioxolo[4,5-f]indolizin-6(7H)-one 
• 914616-21-0 (1S,8S,8aR)-1-((R)-1-(2,4,6-triisopropylphenyl)ethoxy)-8-(triisopropylsilyloxy)-8,8a-dihydroindolizin-3(1H,2H,5H)-one 
• 914616-20-9 (4S,5R)-1-allyl-4-((R)-1-(2,4,6-triisopropylphenyl)ethoxy)-5-((S)-1-(triisopropylsilyloxy)-allyl)pyrrolidin-2-one 

Relevant academic research and scientific papers

Asymmetric [2 + 2] cycloaddition: Total synthesis of (-)-swainsonine and (+)-6-epicastanospermine

(Chemical Equation Presented) An asymmetric total synthesis of (-)-swainsonine and (+)-6-epicastanospermine is described from a common intermediate, which is obtained through diastereoselective [2 + 2] cycloaddition of dichloroketene to a chiral enol ether.

Asymmetric synthesis of (+)-castanospermine through enol ether metathesis-hydroboration/oxidation

An asymmetric synthesis of (+)-castanospermine is presented in which enol ether metathesis-hydroboration/oxidation is used for stereoselective installation of the trans-trans hydroxyl groups on the piperidine ring of the alkaloid.