914638-75-8Relevant academic research and scientific papers
N,N′-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors
Nie, Hong,Widdowson, Katherine L.,Palovich, Michael R.,Fu, Wei,Elliott, John D.,Bryan, Deborah L.,Burman, Miriam,Schmidt, Dulcie B.,Foley, James J.,Sarau, Henry M.,Busch-Petersen, Jakob
, p. 5513 - 5516 (2007/10/03)
A series of N-(2-hydroxy-3-sulfonamidobenzene)-N′-arylcyanoguanidines was prepared. In general, these compounds proved to be potent antagonists of CXCR2 while the selectivity versus CXCR1 ranged from non-selective to >200-fold.
