914642-00-5

Basic information

• Product Name: (2S,2'S,3aR,3'aR,8aR,8'aR)-tetra-tert-butyl 2,2'-bis(acetoxymethyl)-6,6'-dichloro-3a,3'a-bis(phenylselanyl)-3,3a,3',3'a-tetrahydro-5,5'-bipyrrolo[2,3-b]indole-1,1',8,8'(2H,2'H,8aH,8'aH)-tetracarboxylate
• Synonyms: (2S,2'S,3aR,3'aR,8aR,8'aR)-tetra-tert-butyl 2,2'-bis(acetoxymethyl)-6,6'-dichloro-3a,3'a-bis(phenylselanyl)-3,3a,3',3'a-tetrahydro-5,5'-bipyrrolo[2,3-b]indole-1,1',8,8'(2H,2'H,8aH,8'aH)-tetracarboxylate
• CAS NO: 914642-00-5
• Molecular Weight: 1242.02
• Mol File: 914642-00-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,2'S,3aR,3'aR,8aR,8'aR)-tetra-tert-butyl 2,2'-bis(acetoxymethyl)-6,6'-dichloro-3a,3'a-bis(phenylselanyl)-3,3a,3',3'a-tetrahydro-5,5'-bipyrrolo[2,3-b]indole-1,1',8,8'(2H,2'H,8aH,8'aH)-tetracarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,2'S,3aR,3'aR,8aR,8'aR)-tetra-tert-butyl 2,2'-bis(acetoxymethyl)-6,6'-dichloro-3a,3'a-bis(phenylselanyl)-3,3a,3',3'a-tetrahydro-5,5'-bipyrrolo[2,3-b]indole-1,1',8,8'(2H,2'H,8aH,8'aH)-tetracarboxylate(914642-00-5)
• EPA Substance Registry System: (2S,2'S,3aR,3'aR,8aR,8'aR)-tetra-tert-butyl 2,2'-bis(acetoxymethyl)-6,6'-dichloro-3a,3'a-bis(phenylselanyl)-3,3a,3',3'a-tetrahydro-5,5'-bipyrrolo[2,3-b]indole-1,1',8,8'(2H,2'H,8aH,8'aH)-tetracarboxylate(914642-00-5)

Safety Data

• Hazardous Substances Data: 914642-00-5(Hazardous Substances Data)

Upstream product

• 914641-95-5 di-tert-butyl 3,3'-bis((S)-3-acetoxy-2-(tert-butoxycarbonylamino)propyl)-6,6'-dichloro-5,5'-bi(1H-indole)-1,1'dicarboxylate 
• 71098-88-9 N-phenylselanylphthalimide 

Relevant articles and documents

Bidirectional synthesis of the central amino acid of chloptosin

(Chemical Equation Presented) An efficient total synthesis of (2S,2′S,3aR,3′aR,8aR,8′aR)-6,6′-dichloro-3a, 3′a-dihydroxy-1,1′,2,2′,3,3a,3′,3′a,8,8a,8′, 8′a-dodecahydro-5,5′-bipyr-rolo[2,3-b]indole-2,2′- dicarboxylic acid, the central amino acid component of chloptosin (1), is described. Starting from m-chloronitrobenzene, this C2-symmetrical amino acid was synthesized by using a 14-step route, in which a Zinin benzidine rearrangement, intramolecular Heck reaction, and selenocyclization and oxidative deselenation served as key steps. The absolute stereochemistry of the target was confirmed by X-ray single-crystal studies on a key intermediate (17).