914801-95-9Relevant academic research and scientific papers
Antibacterial Agents
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Page/Page column 40-41, (2009/01/20)
The invention provides compounds of formula (I) and salts thereof: R1-L-R2—B wherein R1, L, R2, and B have any of the values defined herein, as well as compositions comprising such compounds, and therapeutic methods comprising the administration of such compounds or salts. The compounds block siderophore production in bacteria and are useful as antibacterial agents.
Design, synthesis, and biological evaluation of β-ketosulfonamide adenylation inhibitors as potential antitubercular agents
Vannada, Jagadeshwar,Bennett, Eric M.,Wilson, Daniel J.,Boshoff, Helena I.,Barry III, Clifton E.,Aldrich, Courtney C.
, p. 4707 - 4710 (2007/10/03)
(Chemical Equation Presented) The antitubercular nucleoside antibiotics 1 and 2 were recently described that inhibit the adenylate-forming enzyme MbtA and disrupt biosynthesis of the virulence-conferring siderophore known as mycobactin in Mycobacterium tu
