91493-43-5 Usage
General Description
2-Hydroxy-6-phenylpyridine-4-carboxylic Acid is a specialized chemical compound. It is characterized by its structure, which includes a pyridine ring, a phenyl group, and a carboxylic acid group. 2-HYDROXY-6-PHENYLPYRIDINE-4-CARBOXYLIC ACID belongs to the class of organic compounds known as hydroxypyridines, which are compounds containing a pyridine ring substituted at one or more positions by a hydroxyl group. As a relatively complex molecular structure, it likely exhibits unique chemical reactions and properties. However, detailed specific information such as its uses, effects, or potential industries in which it could be used is limited or not readily available, indicating that this may be a compound largely of academic interest, used in laboratory research and study.
Check Digit Verification of cas no
The CAS Registry Mumber 91493-43-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,4,9 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91493-43:
(7*9)+(6*1)+(5*4)+(4*9)+(3*3)+(2*4)+(1*3)=145
145 % 10 = 5
So 91493-43-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H9NO3/c14-11-7-9(12(15)16)6-10(13-11)8-4-2-1-3-5-8/h1-7H,(H,13,14)(H,15,16)
91493-43-5Relevant articles and documents
Design and synthesis of disubstituted (4-piperidinyl)-piperazine derivatives as potent acetyl-CoA carboxylase inhibitors
Chonan, Tomomichi,Tanaka, Hiroaki,Yamamoto, Daisuke,Yashiro, Miyoko,Oi, Takahiro,Wakasugi, Daisuke,Ohoka-Sugita, Ayumi,Io, Fusayo,Koretsune, Hiroko,Hiratate, Akira
scheme or table, p. 3965 - 3968 (2010/09/03)
Acetyl-CoA carboxylases (ACCs), the rate limiting enzymes in de novo lipid synthesis, play important roles in modulating energy metabolism. The inhibition of ACC has demonstrated promising therapeutic potential for treating obesity and type 2 diabetes mellitus in transgenic mice and preclinical animal models. We describe herein the structure-based design and synthesis of a novel series of disubstituted (4-piperidinyl)-piperazine derivatives as ACC inhibitors. Our structure-based approach led to the discovery of the indole derivatives 13i and 13j, which exhibited potent in vitro ACC inhibitory activity.
