914933-49-6Relevant academic research and scientific papers
Total synthesis of the potent antifungal agents bengazole C and E
Enriquez-Garcia, Alvaro,Ley, Steven V.
, p. 887 - 900 (2009)
The bengazoles are marine natural products with unique structure, containing two oxazole rings flanking a single carbon. They show very potent antifungal activity. The total syntheses of bengazole C and E are described following a convergent route which involves diastereoselective cycloaddition of an appropriately substituted nitrile oxide with a butane-1,2-diacetal-protected alkenediol as the key step.
