914943-91-2

Usage

Uses

Used in Organic Synthesis:
Tert-butyl 3-ethynylbenzoate is used as a building block for the preparation of various organic compounds, such as pharmaceuticals, agrochemicals, and specialty chemicals. Its high reactivity allows for the introduction of the ethynyl functional group into organic molecules, making it a valuable reagent in chemical reactions.
Used in Pharmaceutical Industry:
Tert-butyl 3-ethynylbenzoate is used as a precursor in the synthesis of other functionalized benzoic acid derivatives with potential applications in the pharmaceutical industry. Its unique structure and reactivity contribute to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, tert-butyl 3-ethynylbenzoate is utilized as a starting material for the synthesis of various agrochemicals, such as pesticides and herbicides. Its versatility in organic synthesis enables the creation of novel compounds with improved efficacy and selectivity.
Used in Specialty Chemicals Industry:
Tert-butyl 3-ethynylbenzoate is also used in the specialty chemicals industry for the production of various specialty chemicals with specific applications. Its unique properties and reactivity make it a valuable component in the synthesis of these specialized compounds.

Upstream product

• 618-51-9 3-Iodobenzoic acid 
• 173406-17-2 tert-butyl 3-iodobenzoate 
• 1393900-84-9 tert-butyl 3-((trimethylsilyl)ethynyl)benzoate 

Downstream Products

• 1393900-85-0 tert-butyl 3-((2-(methylthio)-5-(trifluoromethyl)pyrimidin-4-yl)ethynyl)benzoate 
• 10602-06-9 methyl 3-ethynylbenzoate 
• 1418731-93-7 C₂₄H₂₅F₃N₆O 
• 1393901-00-2 tert-butyl 4-(4-((4-(3-carbamoylphenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate 
• 1393900-99-6 lithium 3-(2-(2-((4-(4-(tert-butoxycarbonyl)piperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoate 
• 1393900-98-5 tert-butyl 4-(4-((4-(3-(methoxycarbonyl)phenethyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate 
• 1393900-97-4 tert-butyl 4-(4-((4-((3-(methoxycarbonyl)phenyl)ethynyl)-5-(trifluoromethyl)pyrimidin-2-yl)amino)phenyl)piperazine-1-carboxylate 
• 1393900-44-1 3-(2-(2-((3-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzamide 
• 1393900-96-3 3-(2-(2-((3-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoic acid 
• 1393900-95-2 tert-butyl 3-(2-(2-((3-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoate 
• 1393900-40-7 3-(2-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzamide 
• 1393900-88-3 tert-butyl 3-(2-(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoate 
• 1393900-87-2 tert-butyl 3-(2-(2-(methylsulfonyl)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoate 
• 1393900-86-1 tert-butyl 3-(2-(2-(methylthio)-5-(trifluoromethyl)pyrimidin-4-yl)ethyl)benzoate 

Relevant academic research and scientific papers

FAK AND FLT3 INHIBITORS

The use of a compound of the formula (I): (Formula (I)) in the preparation of a medicament for treating Acute Myeloid Leukemia or a disease ameliorated by the inhibition of Flt3, or Flt3 and FAK.

FAK INHIBITORS

A compound of the formula (I): where R1 or R2 is a cycle amine group and R5 is an aromatic group with a carbonyl containing substituent for use as a FAK inhibitor.