914955-59-2

Upstream product

• 50-00-0 formaldehyd 
• 1164-16-5 Z-L-Tyr-OH 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 
• 300-39-0 3,5-diiodo-l-tyrosine 
• 60-18-4 L-tyrosine 
• 914955-47-8 N-(benzyloxycarbonyl)-3,5-bis(N-morpholinomethyl)-(S)-tyrosine methyl ester 
• 914955-48-9 N-(benzyloxycarbonyl)-O-acetyl-3,5-bis(acetoxymethyl)-(S)-tyrosine methyl ester 

Relevant academic research and scientific papers

An efficient synthesis of l-3,4,5-trioxygenated phenylalanine compounds from l-tyrosine

A new strategy for the synthesis of l-3,4,5-trioxygenated phenylalanine derivatives from l-tyrosine is developed for the first time. The approach, featuring the transformation of aryl diiodide to bis-phenol via a one-pot procedure including lithiation, boronation, and oxidation, is highly practical. By this robust protocol, N-protected l-3,5-bis(tert-butyldimethylsilyloxy)-4- methoxy-phenylalanine and l-3,4,5-trimethoxy-phenylalanine derivatives were obtained from l-tyrosine in 9 steps with 36-40% overall yields.

Acid-catalyzed synthesis of methylene-bridged (S)-tyrosine - Phenol dimers

(Chemical Equation Presented) The efficient synthesis of 2,2′-arylmethylene dimers from 3-hydroxymethyl or 3-methoxymethyl-5-halo- (S)-tyrosines and para-substituted phenols under acid-catalyzed reaction conditions using either conventional or microwave-a