915020-55-2

Usage

Uses

Used in Pharmaceutical Industry:
BGT226 is used as a chemical intermediate for the development and screening of anti-prostate cancer drugs.
It is utilized in the research and development of pharmaceuticals targeting the PI3K-AKT-mTOR pathway, which is a key signaling mechanism in the growth and survival of prostate cancer cells. By inhibiting this pathway, BGT226 has the potential to contribute to the discovery of effective treatments for prostate cancer.

Upstream product

• 163105-89-3 2-methoxy-pyridine-5-boronic acid 
• 723281-72-9 6-bromo-4-chloro-3-nitroquinoline 
• 193902-87-3 tert-butyl 4-(4-amino-2-(trifluoromethyl)phenyl)piperazine-1-carboxylate 

Relevant academic research and scientific papers

COMPOUNDS AND METHOD FOR BLOCKING TRANSMISSION OF MALARIAL PARASITE

Disclosed are compounds of formula (I) and formula (II): (I) (II) wherein R1, R2, A, and B are as defined herein. Also disclosed is a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing mal

Acid-Promoted Cascade Reaction of N-(4-Chloroquinolin-3-yl)carbamates with Amines: One-Pot Assembly of Imidazo[4,5-c]quinolin-2-ones

An acid-promoted cascade reaction of N-(4-chloroquinolin-3-yl)carbamates with amines is described. This method achieves the formation of two new C–N bonds through an intermolecular amination/intramolecular cyclization reaction sequence. In combination wit

IMIDAZOQUINOLINES AS LIPID KINASE INHIBITORS

The invention relates to novel organic compounds of formula (I) processes for the preparation thereof, the application thereof in a process for the treatment of the human or animal body, the use thereof - alone or in combination with one or more other pharmaceutically active compounds - for the treatment of an inflammatory or obstructive airway disease, such as asthma, disorders commonly occurring in connection with transplantation, or a proliferative disease, such as a tumor disease.