91503-79-6 Hazards Identification
Pictogram(s):
Signal:
Danger
GHS Hazard Statements:
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
Precautionary Statement Codes:
P264, P270, P301+P316, P321, P330, P405, and P501
Hazard Classes and Categories:
Acute Tox. 3 (100%)
91503-79-6 Usage
Uses
Used in Pharmaceutical Industry:
Flurbiprofen Axetil is used as an analgesic for the treatment of mild to moderate pain, such as headaches, menstrual cramps, and musculoskeletal pain. Its anti-inflammatory properties also make it useful for conditions like arthritis and other inflammatory disorders.
Additionally, Flurbiprofen Axetil is used as an antipyretic to reduce fever and associated symptoms. Its effectiveness in managing pain and inflammation makes it a valuable component in the pharmaceutical industry for various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 91503-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,5,0 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 91503-79:
(7*9)+(6*1)+(5*5)+(4*0)+(3*3)+(2*7)+(1*9)=126
126 % 10 = 6
So 91503-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H19FO4/c1-12(19(22)24-14(3)23-13(2)21)16-9-10-17(18(20)11-16)15-7-5-4-6-8-15/h4-12,14H,1-3H3
91503-79-6Relevant academic research and scientific papers
Method for purifying flurbiprofen axetil
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Paragraph 0019-0025, (2021/11/14)
The invention discloses a method for purifying flurbiprofen axetil, a high-pressure preparation method is applied to a flurbiprofen axetil purification process for the first time, and a flurbiprofen axetil purification process which is efficient, stable and easier for industrial production is developed.
Preparation method of flurbiprofen and preparation method of flurbiprofen axetil
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, (2018/10/19)
The invention relates to the field of pharmaceutical chemical synthesis, in particular to a preparation method of flurbiprofen and a preparation method of flurbiprofen axetil. The preparation method of the flurbiprofen comprises the steps of carrying out a Grignard reaction by using 4-bromine-2-fluorine biphenyl as a raw material, carrying out a coupling reaction, and acidizing to obtain the flurbiprofen; the yield is 90%, and the purity is 99.5%; then, the flurbiprofen axetil is prepared by using the flurbiprofen, obtained by the method, as a raw material, the yield reaches up to 90%, and thepurity reaches up to 99.5%. The preparation methods are high in quality controllability and industrial reproducibility.
