91504-12-0

Basic information

• Product Name: {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester
• Synonyms: {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester
• CAS NO: 91504-12-0
• Molecular Weight: 946.078
• Mol File: 91504-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester(91504-12-0)
• EPA Substance Registry System: {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester(91504-12-0)

Safety Data

• Hazardous Substances Data: 91504-12-0(Hazardous Substances Data)

Upstream product

• 64221-82-5 4-(2-acetoxy-(E)-vinyl)-2-azetidinone 
• 64066-60-0 4-(2-acetoxyethyl)-2-azetidinone 
• 64066-62-2 4-(2-hydroxyethyl)azetidin-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 91504-08-4 Carbonic acid 1-{(2R,3S)-1-(tert-butyl-dimethyl-silanyl)-2-[2-(tert-butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-4-oxo-azetidin-3-yl}-ethyl ester 2-nitro-benzyl ester 
• 91504-11-9 {(2R,3S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-hydroxy-acetic acid 2-nitro-benzyl ester 
• 91504-10-8 Carbonic acid 1-{(2R,3S)-2-[2-(tert-butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-4-oxo-azetidin-3-yl}-ethyl ester 2-nitro-benzyl ester 
• 91504-09-5 Carbonic acid 1-[(2S,3R)-2-(2-cyclopropyl-2-hydroxy-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester 2-nitro-benzyl ester 
• 91504-07-3 1-(tert-Butyl-dimethyl-silanyl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-3-(1-hydroxy-ethyl)-azetidin-2-one 
• 91504-05-1 1-(tert-Butyl-dimethyl-silanyl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-2-cyclopropyl-ethyl]-azetidin-2-one 
• 91504-02-8 1-(tert-Butyl-dimethyl-silanyl)-4-(2-trimethylsilanyloxy-ethyl)-azetidin-2-one 
• 91504-03-9 1-(tert-Butyl-dimethyl-silanyl)-4-(2-cyclopropyl-2-hydroxy-ethyl)-azetidin-2-one 
• 91504-01-7 4-(2-Trimethylsilanyloxy-ethyl)-azetidin-2-one 
• 67501-92-2 N-(t-butyldimethylsilyl)-4-(2-hydroxyethyl)-azetidin-2-one 

Downstream Products

• 91504-15-3 (5R,6S)-3-Cyclopropyl-6-[(R)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 2-nitro-benzyl ester 
• 91504-15-3 (5R,6S)-3-Cyclopropyl-6-[(S)-1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 2-nitro-benzyl ester 
• 91504-14-2 {(2R,3S)-2-(2-Cyclopropyl-2-oxo-ethyl)-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 
• 91504-13-1 {(2R,3S)-2-(2-Cyclopropyl-2-hydroxy-ethyl)-3-[1-(2-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid 2-nitro-benzyl ester 

Relevant articles and documents

SYNTHETIC STUDY OF CARBAPENEM ANTIBIOTICS I. (+/-)-2-CYCLOPROPYL-6-(1'-HYDROXYETHYL)-1-CARBAPEN-2-EM-3-CARBOXYLIC ACID

A synthetic scheme extensively utiliing silylation-desilylation reactions to achieve the total synthesis of 2,6-substituted carbapenem antibiotics from readily available azetidinones is reported.An epimeric pair of new 2,6-substituted carbapenems, (+/-)-2