915145-01-6

Basic information

• Product Name: tert-butyl (4-bromo-2,6-dichlorophenyl)carbamate
• Synonyms: tert-butyl (4-bromo-2,6-dichlorophenyl)carbamate
• CAS NO: 915145-01-6
• Molecular Weight: 341.032
• Mol File: 915145-01-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (4-bromo-2,6-dichlorophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (4-bromo-2,6-dichlorophenyl)carbamate(915145-01-6)
• EPA Substance Registry System: tert-butyl (4-bromo-2,6-dichlorophenyl)carbamate(915145-01-6)

Safety Data

• Hazardous Substances Data: 915145-01-6(Hazardous Substances Data)

Upstream product

• 697-88-1 4-bromo-2,6-dichloroaniline 
• 915145-00-5 di-tert-butyl N-(4-bromo-2,6-dichlorophenyl)iminodicarboxylate 

Relevant articles and documents

Proton mobility in 2-substituted 1,3-dichlorobenzenes: "ortho" or "meta" metalation?

Nine 1,3-dichlorobenzene congeners were selected as model compounds to assess the relative rates of proton abstraction from 4- and 5-positions ("ortho" vs. "meta" metalation). Using lithium 2,2,6,6-tetramethylpiperidide as the basic reagent, the chlorine-adjacent 4-position underwent metalation exclusively. In contrast, attack at the chlorine-remote 5-posi" tion became significant even in the case of moderately sized 2-substituents (such as dimethylamino or ethyl) when secbutyllithium was employed. The "ortho/para" (4-/5-) ratios ranged from 80:20 to 65:35. The more pronounced "meta-orienting" effect of silicon as opposed to carbon substituents can be attributed to dissimilarities in the n polarization of the aromatic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.