915158-67-7

Basic information

• Product Name: 4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol
• Synonyms: 4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol
• CAS NO: 915158-67-7
• Molecular Weight: 434.532
• Mol File: 915158-67-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol(915158-67-7)
• EPA Substance Registry System: 4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol(915158-67-7)

Safety Data

• Hazardous Substances Data: 915158-67-7(Hazardous Substances Data)

Upstream product

• 915158-65-5 (1R,2R,3R,4S)-4-nitrobenzoic acid 4-[4-(4-benzyloxy-3-methoxyphenyl)-1-hydroxy-4-methoxymethoxy-2,3-dimethylbutyl]-2-methoxyphenyl ester 
• 915158-64-4 (1R,2R,3R,4S)-4-[4-(4-benzyloxy-3-methoxyphenyl)-1-hydroxy-4-methoxymethoxy-2,3-dimethylbutyl]-2-methoxyphenol 
• 915158-62-2 (2R,3R,4R)-4-(4-allyloxy-3-methoxyphenyl)-4-(tert-butyldimethylsilanyloxy)-2,3-dimethylbutyraldehyde 
• 915158-66-6 4-Nitro-benzoic acid 4-[(2S,3R,4R,5S)-5-(4-benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenyl ester 

Downstream Products

• 915158-75-7 (S)-1-Benzo[1,3]dioxol-5-yl-2-[4-((2S,3R,4R,5S)-5-{4-[(1R,2R)-2-(3,4-dimethoxy-phenyl)-2-hydroxy-1-methyl-ethoxy]-3-methoxy-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenoxy]-propan-1-one 
• 915158-69-9 (R)-1-(3,4-Dimethoxy-phenyl)-2-[4-((2S,3R,4R,5S)-5-{4-[(R)-2-(3,4-dimethoxy-phenyl)-1-methyl-2-oxo-ethoxy]-3-methoxy-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenoxy]-propan-1-one 
• 915158-84-8 (S)-2-[4-((2S,3R,4R,5S)-5-{4-[(1R,2R)-2-(3,4-Dimethoxy-phenyl)-2-hydroxy-1-methyl-ethoxy]-3-methoxy-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenoxy]-N-methoxy-N-methyl-propionamide 
• 915158-88-2 (R)-2-(4-{(2S,3R,4R,5S)-5-[4-((1R,2R)-2-Benzo[1,3]dioxol-5-yl-2-hydroxy-1-methyl-ethoxy)-3-methoxy-phenyl]-3,4-dimethyl-tetrahydro-furan-2-yl}-2-methoxy-phenoxy)-N-methoxy-N-methyl-propionamide 
• 915158-82-6 (1R,2R)-1-Benzo[1,3]dioxol-5-yl-2-{4-[(2S,3R,4R,5S)-5-(4-benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-propan-1-ol 
• 915158-74-6 (S)-2-[4-((2S,3R,4R,5S)-5-{4-[(1R,2R)-2-(3,4-Dimethoxy-phenyl)-2-hydroxy-1-methyl-ethoxy]-3-methoxy-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenoxy]-propionic acid methyl ester 
• 915158-72-4 (R)-2-(4-{(2S,3R,4R,5S)-5-[4-((1R,2R)-2-Benzo[1,3]dioxol-5-yl-2-hydroxy-1-methyl-ethoxy)-3-methoxy-phenyl]-3,4-dimethyl-tetrahydro-furan-2-yl}-2-methoxy-phenoxy)-propionic acid methyl ester 
• 915158-83-7 (1R,2R)-2-{4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-1-(3,4-dimethoxy-phenyl)-propan-1-ol 
• 915158-81-5 (2R,2''S,3''R,4''R,5''S)-1-benzo[1,3]dioxol-5-yl-2-{4'-[5''-(4'''-benzyloxy-3'''-methoxyphenyl)-3'',4''-dimethyl-tetrahydro-furan-2''-yl]-2'-methoxy-phenoxy}-propan-1-ol 
• 915158-73-5 (R)-2-{4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-1-(3,4-dimethoxy-phenyl)-propan-1-one 
• 915158-71-3 4-{(2S,3R,4R,5S)-5-[4-((1R,2R)-2-Benzo[1,3]dioxol-5-yl-2-hydroxy-1-methyl-ethoxy)-3-methoxy-phenyl]-3,4-dimethyl-tetrahydro-furan-2-yl}-2-methoxy-phenol 
• 88497-86-3 sancerneol 
• 915158-79-1 (R)-N-Methoxy-2-[2-methoxy-4-((2S,3R,4R,5S)-5-{3-methoxy-4-[(R)-1-(methoxy-methyl-carbamoyl)-ethoxy]-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-phenoxy]-N-methyl-propionamide 
• 915158-80-4 (R)-2-{4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-N-methoxy-N-methyl-propionamide 

Relevant articles and documents

Total synthesis and stereochemical confirmation of 2,5-diaryl-3,4- dimethyltetrahydrofuran lignans: (+)-Fragransin A2, (+)-galbelgin, (+)-talaumidin, (-)-saucernetin and (-)-verrucosin

A new ring closure to tetrasubstituted tetrahydrofurans from the intramolecular attack of an OMOM ether onto a benzylic mesylate proceeds through a quinonoid intermediate or by direct SN2 displacement. The synthesis of diastereomeric biological