915190-39-5Relevant articles and documents
Development of synthetic strategies for the construction of pyrido[4,3-d]-pyrimidine libraries - The discovery of a new class of PDE-4 inhibitors
Jang, Mi-Yeon,De Jonghe, Steven,Gao, Ling-Jie,Rozenski, Jef,Herdewijn, Piet
, p. 4257 - 4269 (2006)
The synthesis of a pyrido[4,3-d]pyrimidine library from 4,6-diamino-2-bromonicotinamide and 4,6-diaminonicotinamide is described. A systematic variation of the substituents at positions 2, 4, 5 and 7 of the pyrido[4,3-d]pyrimidine scaffold was carried out