915200-41-8Relevant academic research and scientific papers
First evidence of proline acting as a bifunctional catalyst in the Baylis-Hillman reaction between alkyl vinyl ketones and aryl aldehydes
Gruttadauria, Michelangelo,Giacalone, Francesco,Lo Meo, Paolo,Marculescu, Adriana Mossuto,Riela, Serena,Noto, Renato
, p. 1589 - 1596 (2008)
Proline in the presence of sodium hydrogen carbonate has been found to be an effective catalyst for the Baylis-Hillman reaction between methyl or ethyl vinyl ketone and aryl aldehydes. Screening of several amine catalysts showed that an ionizable carboxyl
Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis
Cocco, Mattia,Garella, Davide,Di Stilo, Antonella,Borretto, Emily,Stevanato, Livio,Giorgis, Marta,Marini, Elisabetta,Fantozzi, Roberto,Miglio, Gianluca,Bertinaria, Massimo
, p. 10366 - 10382 (2015/02/19)
Pyroptosis is a caspase-1-dependent pro-inflammatory form of programmed cell death implicated in the pathogenesis of autoinflammatory diseases as well as in disorders characterized by excessive cell death and inflammation. Activation of NLRP3 inflammasome
