915201-07-9

Basic information

• Product Name: 3-CHLORO-5-METHOXYBENZENEBORONIC ACID
• Synonyms: 3-CHLORO-5-METHOXYBENZENEBORONIC ACID;3-Chloro-5-methoxyphenylboronic acid
• CAS NO: 915201-07-9
• Molecular Formula: C₇H₈BClO₃
• Molecular Weight: 186.40062
• Mol File: 915201-07-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 185-189°C
• Boiling Point: 359.6 °C at 760 mmHg
• Flash Point: 171.3 °C
• Appearance: /
• Density: 1.32 g/cm³
• Vapor Pressure: 8.51E-06mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 7.12±0.10(Predicted)
• Water Solubility: Insoluble in water.
• CAS DataBase Reference: 3-CHLORO-5-METHOXYBENZENEBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-5-METHOXYBENZENEBORONIC ACID(915201-07-9)
• EPA Substance Registry System: 3-CHLORO-5-METHOXYBENZENEBORONIC ACID(915201-07-9)

Safety Data

• Hazardous Substances Data: 915201-07-9(Hazardous Substances Data)

Usage

Uses

It is used as an active pharmaceutical intermediate.

InChI:InChI=1/C7H8BClO3/c1-12-7-3-5(8(10)11)2-6(9)4-7/h2-4,10-11H,1H3

Upstream product

• 929626-16-4 2-(3-chloro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 2845-89-8 1-chloro-3-methoxy-benzene 

Downstream Products

• 1621256-03-8 (4S,5R)-5-(3,5-bis(trifluoromethyl)phenyl)-3-((2-(3-chloro-5-methoxyphenyl)-5,5-dimethylcyclohex-1-enyl)methyl)-4-methyloxazolidin-2-one 
• 1300584-68-2 2-(1-(4-amino-3-(3-chloro-5-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-(3-fluorophenyl)-4H-chromen-4-one 
• 1300584-66-0 2-(1-(4-amino-3-(3-chloro-5-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-(3-fluorophenyl)-4H-chromen-4-one 
• 1186024-79-2 2-(3-chloro-5-methoxyphenyl)quinoline 

Relevant articles and documents

One-pot synthesis of arylboronic acids and aryl trifluoroborates by Ir-catalyzed borylation of arenes

(Chemical Equation Presented) The synthesis of arylboronic acids and aryl trifluoroborates in a one-pot sequence by Ir-calalyzed borylation of arenes is reported. To prepare the arylboronic acids, the Ir-catalyzed borylation is followed by oxidative cleavage of the boronic ester with NaIO4. To prepare the aryltrifluoroborate, the Ir-catalyzed borylation is followed by displacement of pinacol by KHF2. These two-step sequences give products that are more reactive toward subsequent chemistry than the initially formed pinacol boronates.