915369-95-8

Basic information

• Product Name: 4-chloro-8-methylsulfanyl-6-nitro-quinoline-3-carbonitrile
• Synonyms: 4-Chlor-8-(methylsulfanyl)-6-nitrochinolin-3-carbonitril; 4-chloro-8-(methylsulfanyl)-6-nitroquinoline-3-carbonitrile
• CAS NO: 915369-95-8
• Molecular Formula: C₁₁H₆ClN₃O₂S
• Molecular Weight: 279.7
• Mol File: 915369-95-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 480.9°C at 760 mmHg
• Flash Point: 244.6°C
• Density: 1.55g/cm³
• Vapor Pressure: 2.08E-09mmHg at 25°C
• Refractive Index: 1.708
• PKA: -3.15±0.44(Predicted)
• CAS DataBase Reference: 4-chloro-8-methylsulfanyl-6-nitro-quinoline-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-8-methylsulfanyl-6-nitro-quinoline-3-carbonitrile(915369-95-8)
• EPA Substance Registry System: 4-chloro-8-methylsulfanyl-6-nitro-quinoline-3-carbonitrile(915369-95-8)

Safety Data

• Hazardous Substances Data: 915369-95-8(Hazardous Substances Data)

Relevant articles and documents

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor α (TNF-α) production: Selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3- carbonitriles

Tumor progression loci-2 (Tpl2) (Cot/MAP3K8) is a serine/threonine kinase in the MAP3K family directly upstream of MEK. Recent studies using Tpl2 knockout mice have indicated an important role for Tpl2 in the lipopolysaccharide (LPS) induced production of