915394-29-5

Basic information

• Product Name: 2-(3-aminophenyl)-2-methylpropanenitrile
• Synonyms: 2-(3-aminophenyl)-2-methylpropanenitrile
• CAS NO: 915394-29-5
• Molecular Formula: C₁₀H₁₂N₂
• Molecular Weight: 160
• Mol File: 915394-29-5.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-(3-aminophenyl)-2-methylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-aminophenyl)-2-methylpropanenitrile(915394-29-5)
• EPA Substance Registry System: 2-(3-aminophenyl)-2-methylpropanenitrile(915394-29-5)

Safety Data

• Hazardous Substances Data: 915394-29-5(Hazardous Substances Data)

Usage

General Description

2-(3-aminophenyl)-2-methylpropanenitrile is a chemical compound characterized by its structure, which includes an aminophenyl group attached to a methylpropane with a nitrile group. The aminophenyl part involves an amino group (-NH2) attached to a phenyl ring, which is a cyclic group of atoms with the formula C6H5. The methylpropane portion refers to a three-carbon alkane molecule with one methyl group, which is a compound with the formula CH3. Meanwhile, the nitrile group is a functional group made of a carbon triple-bonded to a nitrogen. This chemical can be used in various reactions and processes in the field of chemistry, although specific applications can vary depending on additional factors such as the presence and nature of other compounds in a reaction mixture. Full safety and handling measures should be employed due to potential hazards associated with chemicals of this nature.

Upstream product

• 872091-85-5 methyl 3-(1-cyano-1-methylethyl)benzoate 
• 915394-28-4 2-methyl-2-(3-nitrophenyl)propanenitrile 
• 90433-20-8 2-(3-bromo-phenyl)-2-methyl-propionitrile 
• 872091-00-4 3-(1-cyano-1-methylethyl)benzoic acid 
• 951627-60-4 tert-butyl [3-(1-cyano-1-methylethyl)phenyl]carbamate 

Downstream Products

• 1240349-35-2 C₃₂H₃₅N₇O₂S 
• 951627-49-9 N-[3-(1-cyano-1-methylethyl)phenyl]-4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]benzamide 

Relevant articles and documents

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

ISOQUINOLINE-5-CARBOXAMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

A compound selected from the group consisting of an isoquinoline-5-carboxamide derivative of formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate and a solvate thereof is effective for the prevention or treatment of diseases associated with abnormal cell growth, which are caused by abnormal activation of a protein kinases.

QUINAZOLINONE DERIVATIVES HAVING B-RAF INHIBITORY ACTIVITY

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.