915394-29-5

Usage

Uses

Used in Chemical Synthesis:
2-(3-aminophenyl)-2-methylpropanenitrile is used as a building block in chemical synthesis for the production of various organic compounds. Its unique structure allows it to participate in a range of reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(3-aminophenyl)-2-methylpropanenitrile is used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its presence in the molecular structure can contribute to the development of new drugs with specific therapeutic properties, such as analgesics, anti-inflammatory agents, or other therapeutic agents.
Used in Agrochemical Industry:
2-(3-aminophenyl)-2-methylpropanenitrile is used as a key intermediate in the synthesis of agrochemicals, including pesticides and herbicides. Its unique structure can be modified to create compounds with specific pesticidal or herbicidal properties, contributing to the development of more effective and targeted crop protection products.
Used in Research and Development:
In the field of research and development, 2-(3-aminophenyl)-2-methylpropanenitrile is used as a starting material or a reagent in various chemical reactions to explore new synthetic pathways and develop novel compounds with potential applications in various industries.
Used in Material Science:
2-(3-aminophenyl)-2-methylpropanenitrile can be used in material science for the development of new polymers, coatings, or other materials with specific properties. Its unique structure can be incorporated into the backbone of these materials to impart desired characteristics, such as improved strength, flexibility, or chemical resistance.

Upstream product

• 951627-60-4 tert-butyl [3-(1-cyano-1-methylethyl)phenyl]carbamate 
• 872091-85-5 methyl 3-(1-cyano-1-methylethyl)benzoate 
• 915394-28-4 2-methyl-2-(3-nitrophenyl)propanenitrile 
• 90433-20-8 2-(3-bromo-phenyl)-2-methyl-propionitrile 
• 872091-00-4 3-(1-cyano-1-methylethyl)benzoic acid 

Downstream Products

• 1240349-35-2 C₃₂H₃₅N₇O₂S 
• 951627-49-9 N-[3-(1-cyano-1-methylethyl)phenyl]-4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]benzamide 

Relevant academic research and scientific papers

(PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER

The present invention relates to pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment and/or prevention of a proliferation disorder associated with ΤGFβR1 activity, such as a cancer or fibrosis. The invention provides compounds of Formula (I) and Formula (II) as further described herein having an acidic moiety that enhances tissue specificity for targeted tissues and organs. The invention includes pharmaceutical compositions, pharmaceutical combinations, and methods of use of these compounds for treating conditions including cancer or fibrosis.

ISOQUINOLINE-5-CARBOXAMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

A compound selected from the group consisting of an isoquinoline-5-carboxamide derivative of formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate and a solvate thereof is effective for the prevention or treatment of diseases associated with abnormal cell growth, which are caused by abnormal activation of a protein kinases.

ISOQUINOLINE-5-CARBOXAMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

A compound selected from the group consisting of an isoquinoline-5-carboxamide derivative of formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate and a solvate thereof is effective for the prevention or treatment of diseases associated with abnormal cell growth, which are caused by abnormal activation of a protein kinases.

FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF

The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof. A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.

QUINAZOLINONE DERIVATIVES HAVING B-RAF INHIBITORY ACTIVITY

The invention relates to chemical compounds of the formula (I) or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE

The present invention provides new compounds of formula I, wherein Q, R1, R2, R4, R5, R6, Xi, R7, R8, M and G1 nare defined as in formula I; invention compounds are modulators of follicle-stimulating hormone - ("FSH") which are useful for male and female contraception as well as other disorders modulated by FSH receptor.

HETEROARYL DERIVATIVES AS PROTEIN KINASE INHIBITORS

Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

SUBSTITUTED QUINAZOLINES WITH ANTI-CANCER ACTIVITY

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B Raf inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.

QUINAZOLIN-4-ONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The invention relates to chemical compounds of the formula (I): or pharmaceutically acceptable salts thereof, which possess B-Raf inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.

ANTIFUNGAL AGENTS

Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.