91548-69-5Relevant academic research and scientific papers
Functional analysis of phenylalanine 365 in hopene synthase, a conserved amino acid in the families of squalene and oxidosqualene cyclases
Hoshino, Tsutomu,Sato, Tsutomu
, p. 2005 - 2006 (1999)
Two bicyclic products were accumulated by the mutant F365A, showing the amino acid residue is located close to the transient C-8 carbocation intermediate in the active site cavity; the mutants of F365Y and F365W significantly accelerated the cyclization reaction at low temperatures.
