91573-14-7Relevant academic research and scientific papers
A cascade Claisen rearrangement/o-quinone methide formation/electrocyclization approach to 2H-chromenes
Song, Liyan,Huang, Fang,Guo, Liwen,Ouyang, Ming-An,Tong, Rongbiao
supporting information, p. 6021 - 6024 (2017/07/10)
A new approach has been developed for the synthesis of 8-substituted 2H-chromenes, featuring a novel cascade aromatic Claisen rearrangement/o-quinone methide formation/6π-electrocyclization. This new method was demonstrated with 28 examples tolerating different substitutions at alkenes, allylic and aromatic ring and with total syntheses of three 2H-chromene natural products.
