915775-99-4

Upstream product

• 90087-64-2 1-(1-nitroethyl)cyclohexene 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 915775-90-5 1-cyclohexenyl-N,N-bis(tert-butyldimethylsilyloxy)ethenamine 
• 623-48-3 ethyl iodoacetae 

Relevant academic research and scientific papers

Radical alkylation of bis(silyloxy)enamine derivatives of organic nitro compounds

(Chemical Equation Presented) Alkylation β to a nitro group by radical chemistry is made possible by initial conversion of the organic nitro compound into a bis(silyloxy)enamine (see scheme; TBSOTf=tert-butyldimethylsilyl trifluoromethanesulfonate). An advantage of the method is the simultaneous conversion of the nitro group into a synthetically useful oxime ether group.