915922-73-5 Usage
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 4003794 is used as a chemical intermediate for the preparation of imidazolinylnicotinic acids and esters and related compounds. These synthesized compounds exhibit herbicidal properties, making them useful in the development of effective herbicides for agricultural and horticultural applications.
Used in Agrochemical Industry:
In the agrochemical industry, CHEMBRDG-BB 4003794 plays a crucial role in the synthesis of herbicidal agents that help control and manage unwanted plant growth. These herbicides are designed to target specific weeds without causing harm to the desired crops, ensuring a healthy and productive agricultural environment.
Check Digit Verification of cas no
The CAS Registry Mumber 915922-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,5,9,2 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 915922-73:
(8*9)+(7*1)+(6*5)+(5*9)+(4*2)+(3*2)+(2*7)+(1*3)=185
185 % 10 = 5
So 915922-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H6ClNO2/c11-7-3-1-2-6-4-5-8(10(13)14)12-9(6)7/h1-5H,(H,13,14)
915922-73-5Relevant academic research and scientific papers
Repurposing an Aldolase for the Chemoenzymatic Synthesis of Substituted Quinolines
Fansher, Douglas J.,Granger, Richard,Kaur, Satinderpal,Palmer, David R. J.
, p. 6939 - 6943 (2021/06/28)
Quinoline derivatives are important natural products and pharmaceuticals, but their synthesis can be challenging due to poor yields, harsh reaction conditions, and instability of starting materials. Here we report the chemoenzymatic synthesis of quinaldic acids under mild conditions using an aldolase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (NahE, or HBPA). A series of 2-aminobenzaldehydes derived from reduction of the corresponding nitro analogue were reacted with pyruvate in the presence of NahE to give substituted quinolines in up to 93% isolated yield. This reaction differs from the aldol condensation catalyzed by NahE in vivo, instead resembling the heterocycle formation catalyzed by its homologue, dihydrodipicolinate synthase.
