91600-12-3 Usage
Uses
Used in Pharmaceutical Applications:
1-(4-fluorobenzyl)piperidin-3-ol is used as a therapeutic agent for the treatment of [application reason] depression and anxiety. Its psychoactive properties make it a subject of interest in medicinal chemistry and neuroscience research, with potential implications for developing novel treatments for these conditions.
Used in Research and Development:
In the field of neuroscience, 1-(4-fluorobenzyl)piperidin-3-ol is used as a research compound to study the effects of psychoactive substances on the brain and behavior. This helps in understanding the underlying mechanisms of depression, anxiety, and other related conditions, ultimately contributing to the development of more effective treatments.
Used in Regulatory and Forensic Applications:
Due to its association with drug abuse, 1-(4-fluorobenzyl)piperidin-3-ol is used in regulatory and forensic applications for the identification and monitoring of controlled substances. This aids in the enforcement of drug control policies and the investigation of related criminal activities.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, 1-(4-fluorobenzyl)piperidin-3-ol serves as a key compound for the synthesis of new drugs and the study of their interactions with biological targets. Its unique structure and pharmacological properties make it a valuable tool in the design and development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 91600-12-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,6,0 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 91600-12:
(7*9)+(6*1)+(5*6)+(4*0)+(3*0)+(2*1)+(1*2)=103
103 % 10 = 3
So 91600-12-3 is a valid CAS Registry Number.
91600-12-3Relevant academic research and scientific papers
Design and synthesis of Rho kinase inhibitors (II)
Iwakubo, Masayuki,Takami, Atsuya,Okada, Yuji,Kawata, Takehisa,Tagami, Yoshimichi,Ohashi, Hiroshi,Sato, Motoko,Sugiyama, Terumi,Fukushima, Kayoko,Iijima, Hiroshi
, p. 350 - 364 (2008/02/04)
In a previous study, we identified several structurally unrelated scaffolds of the Rho kinase inhibitor using pharmacophore information obtained from the results of a high-throughput screening and structural information from a homology model of Rho kinase. 1H-Indazole is one of the candidate scaffolds on which a new series of potent Rho kinase inhibitors could be developed. In this study, the detailed structure-activity relationship of 1H-indazole analogues was studied. During this study, we found that the cell-free enzyme inhibitory potential of Rho kinase inhibitors having the 1H-indazole scaffold did not necessarily correlate with their inhibitory potential toward the chemotaxis of cultured cells. The choice of the linker substructure was shown to be an important factor for the 1H-indazole analogues to inhibit the chemotaxis of cells. Optimization of the 1H-indazole inhibitors with respect to the in vitro inhibition of monocyte chemotaxis induced by MCP-1 was carried out. The inhibitory potential was improved both in the cell-free enzyme assay and in the chemotaxis assay.
