916084-84-9Relevant academic research and scientific papers
Molecular probe for enzymatic activity with dual output
Danieli, Eyal,Shabat, Doron
, p. 7318 - 7324 (2007)
A novel molecular probe for enzymatic activity with a dual output detection-mode has been developed. The probe effectively detected the presence of the bacterial protease penicillin-G-amidase; a single cleavage by the enzyme initiated the fragmentation of
Receiver-amplifier, self-immolative dendritic device
Amir, Roey J.,Danieli, Eyal,Shabat, Doron
, p. 812 - 821 (2007/10/03)
Self-immolative dendrimers disassemble through a domino-like chain fragmentation initiated by a single cleavage at the dendrimer core. We have designed and synthesized dendritic molecules that resemble dendritic architectures present in nature. The unique
Multi-triggered self-immolative dendritic compounds
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Page/Page column 29; sheet 14, (2010/11/24)
Novel self-immolative dendritic compounds which have a plurality of cleavable trigger units and hence can release a chemical moiety at their focal point upon a multi-triggering mechanism are disclosed. The novel self-immolative dendritic compounds are gated by a molecular logic gate, being either an AND or OR logic gate and hence can be beneficially used in a variety of biological, chemical and physical applications. Processes of preparing, compositions containing and methods utilizing the novel dendritic compounds are further disclosed.
