91613-49-9Relevant academic research and scientific papers
Gold(III)-catalyzed 1,4-nucleophilic addition: Facile approach to prepare 2-amino-1,4-naphthalenedione and 6-amino-5,8-quinolinedione derivatives
Jiang, Chunhui,Wang, Shaozhong
experimental part, p. 1099 - 1102 (2009/10/14)
An efficient approach is developed to prepare different 2-amino-1,4-naphthalenedione and 6-amino-5,8-quinolinedione derivatives regioselectively by Au(III)-catalyzed 1,4-nucleophilic addition and subsequent oxidation. A wide variety of primary, secondary, and aromatic amines, as well as allylamine and 2-butynylamine are well tolerated under the mild conditions to give products in moderate to good yields. Georg Thieme Verlag Stuttgart.
Regioselective 6-Amination and 6-Arylation of 5,8-Quinolinedione Promoted by Metal Ions
Yoshida, Katsuhira,Ishiguro, Miwa,Honda, Hiroyuki,Yamamoto, Mayumi,Kubo, Yuji
, p. 4335 - 4340 (2007/10/02)
The effects of some metal ions on the amination and arylation of 5,8-quinolinedione (1) and on the amine displacement of 6-piperidino-5,8-quinolinedione have been investigated.The reaction of 1 with various amines in chloroform or ethanol was specifically
Quinoline quinones and anti-asthmatic use thereof
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, (2008/06/13)
This invention relates to a class of quinoline quinones, which are useful for the therapy of immediate hypersensitivity reactions, such as asthma, and in treating any condition characterized by excessive release of leukotrienes. This invention also includes a method for treating these conditions, which comprises administering to animals, including humans, an effective dose of the quinoline quinone compounds. A further part of this invention is pharmaceutical formulations containing these pharmacologically-active compounds.
