916154-25-1Relevant academic research and scientific papers
Sulfanyl radical promoted C4′-C5′ bond scission of 5′-oxo-3′,4′-didehydro-2′,3′-dideoxynucleosides
Navacchia, Maria Luisa,Montevecchi, Pier Carlo
, p. 3754 - 3756 (2008/09/18)
The synthesis of C5'-aldehydes 1a,b and preliminary results concerning their reactivity under radical conditions was analyzed. Treatment of C5'-aldehydes 4a, b under mildly basic conditions led to the formation of 3' 4' -didehydroaldehydes 1a, b and furfu
Nucleoside 5′-C-phosphonates: reactivity of the α-hydroxyphosphonate moiety
Králíková, ?árka,Budě?ínky, Milo?,Masojídková, Milena,Rosenberg, Ivan
, p. 4917 - 4932 (2007/10/03)
We found that various dialkyl phosphites, dialkyl trimethylsilyl phosphites, and tris-trimethylsilyl phosphite reacted smoothly with nucleoside 5′-aldehydes to afford epimeric nucleoside 5′-C-phosphonates in high yields. A number of these compounds in bot
