916155-48-1Relevant academic research and scientific papers
Stereospecific anti SE2′ fluorination of allenylsilanes: Synthesis of enantioenriched propargylic fluorides
Carroll, Laurence,McCullough, Samantha,Rees, Tom,Claridge, Timothy D. W.,Gouverneur, Veronique
supporting information; experimental part, p. 1731 - 1733 (2008/10/09)
The electrophilic fluorodesilylation of enantioenriched allenylsilanes proceeds with efficient transfer of chirality. The silylation-fluorination of propargylic alcohols occurs with overall retention of stereochemistry, a result consistent with a stereosp
Synthesis of propargylic fluorides from allenylsilanes
Carroll, Laurence,Pacheco, Ma. Carmen,Garcia, Ludivine,Gouverneur, Veronique
, p. 4113 - 4115 (2007/10/03)
Allenylsilanes reacted at room temperature in acetonitrile with Selectfluor, an electrophilic fluorinating reagent, to give secondary propargylic fluorides in moderate to good yields; mechanistically, a side-product resulting from a 1,2-silyl shift testifies to the presence of a cationic intermediate. The Royal Society of Chemistry 2006.
