916219-93-7

Basic information

• Product Name: Butanedioic acid, 2-[4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]phenyl]-, 4-methyl ester, (2S)-
• CAS NO: 916219-93-7
• Molecular Formula: C25H21F3O5
• Molecular Weight: 458.434
• Mol File: 916219-93-7.mol

Chemical Properties

• CAS DataBase Reference: Butanedioic acid, 2-[4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]phenyl]-, 4-methyl ester, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, 2-[4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]phenyl]-, 4-methyl ester, (2S)-(916219-93-7)
• EPA Substance Registry System: Butanedioic acid, 2-[4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]phenyl]-, 4-methyl ester, (2S)-(916219-93-7)

Safety Data

• Hazardous Substances Data: 916219-93-7(Hazardous Substances Data)

Downstream Products

• 916219-97-1 (S)-methyl 3-(4-hydroxyphenyl)-3-(2-methyl-2H-1,2,4-triazol-3-yl)propanoate 
• 929713-33-7 (S)-3-(1-methyl-1H-tetrazol-5-yl)-3-[4-(4'-trifluoromethylbiphenyl-3-ylmethoxy)phenyl]propionic acid 
• 916219-99-3 (S)-methyl 3-(4-hydroxyphenyl)-3-(1-methyl-1H-tetrazol-5-yl)propanoate 
• 916219-71-1 (S)-3-[4-(4'-chloro-2'-methylbiphenyl-3-ylmethoxy)phenyl]-3-(1-methyl-1H-tetrazol-5-yl)propionic acid 
• 916219-87-9 (S)-3-(1-Methyl-1H-tetrazol-5-yl)-3-{4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid 
• 916219-96-0 C₂₅H₂₂F₃NO₄ 
• 916219-98-2 C₂₆H₂₄F₃NO₄ 
• 916219-94-8 C₂₇H₂₆F₃NO₄ 

Relevant articles and documents

Optimization of GPR40 agonists for type 2 diabetes

GPR40 (FFA1 and FFAR1) has gained significant interest as a target for the treatment of type 2 diabetes. TAK-875 (1), a GPR40 agonist, lowered hemoglobin A1c (HbA1c) and lowered both postprandial and fasting blood glucose levels in type 2 diabetic patient