91622-61-6Relevant academic research and scientific papers
Synthesis of 3-aryl-4-(N-aryl)aminocoumarins via photoredox arylation and the evaluation of their biological activity
Carneiro, Leonardo S.A.,Almeida-Souza, Fernando,Lopes, Yanne S.C.,Novas, Rachel C.V.,Santos, Kaique B.A.,Ligiero, Carolina B.P.,Calabrese, Kátia da S.,Buarque, Camilla D.
, (2021/07/22)
A new series of 3-aryl-4-(N-aryl)aminocoumarins was synthesized in two steps starting from the natural product 4-hydroxycoumarin using the photoredox catalysis for the key step. These conditions reactions allowed to make C[sbnd]C bonds is up to 95% yields
Transition-metal free C(sp2)-C(sp2) bond formation: Arylation of 4-aminocoumarins using arynes as an aryl source
Sharma, Abhilash,Gogoi, Pranjal
, p. 9014 - 9025 (2019/10/28)
A mild, efficient and transition-metal free synthetic strategy has been developed for the α-arylation of 4-aminocoumarins. This synthetic strategy proceeds via C(sp2)-C(sp2) bond formation between 4-aminocoumarins and aryne precursors in a single step by simple treatment with a fluoride source in the absence of a metal-catalyst. Moreover, this methodology affords good yields of 4-amino-3-arylcoumarin derivatives bearing halide functionality.
Synthesis of Indoles and Isoquinolones from Phenylmalonate Heterocycles
Stadlbauer, Wolfgang,Kappe, Thomas
, p. 467 - 476 (2007/10/02)
A new synthesis of the indole system has been achieved by cyclodehydrogenation of amino phenylmalonate heterocycles.Thus, the 4-amino coumarins 1a,b or the 4-amino-2-quinolones 1c-g are converted to the indoles 2 with palladium on charcoal in boiling diph
