916225-63-3Relevant academic research and scientific papers
Efficient synthesis of an α(2,9) trisialic acid by one-pot glycosylation and polymer-assisted deprotection
Tanaka, Hiroshi,Tateno, Yusuke,Nishiura, Yuji,Takahashi, Takashi
supporting information; experimental part, p. 5597 - 5600 (2009/06/23)
(Chemical Equation Presented) An efficient synthesis of α(2,9) trisialic acid has been achieved via one-pot glycosylation and polymer-assisted deprotection. The synthesis involves chemo- and regioselective α-sialylation of ethylthiosialoside with the S-be
Efficient polymer-assisted strategy for the deprotection of protected oligosaccharides
Tanaka, Hiroshi,Ishida, Tadasuke,Matoba, Nobuatsu,Tsukamoto, Hirokazu,Yamada, Haruo,Takahashi, Takashi
, p. 6349 - 6352 (2007/10/03)
(Chemical Equation Presented) New strategies in sugar synthesis: A prelinker containing a dihydropyranyl moiety and an activated ester can be attached to a sugar, which is then loaded onto an amino-modified support by amidation. Standard protecting-group manipulations are possible. Final cleavage of the linker under mildly acidic conditions provides the fully deprotected oligosaccharides. TFA=trifluoroacetic acid.
