91632-23-4

Usage

Uses

Used in Pharmaceutical Industry:
Benzeneacetic acid, 4-bromo-alpha-formyl-, ethyl ester is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the creation of complex molecular structures. Its unique functional groups contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, Benzeneacetic acid, 4-bromo-alpha-formyl-, ethyl ester is utilized as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its reactivity allows for the synthesis of compounds with targeted biological activities to control or eliminate pests and weeds.
Used in Fine Chemicals Industry:
Benzeneacetic acid, 4-bromo-alpha-formyl-, ethyl ester is employed as a versatile intermediate in the synthesis of fine chemicals, including fragrances, dyes, and other specialty chemicals. Its functional groups enable the development of a wide range of chemical products with specific applications in various industries.
Used in Research Applications:
In research settings, Benzeneacetic acid, 4-bromo-alpha-formyl-, ethyl ester is used as a valuable compound for exploring new chemical reactions and synthetic pathways. Its unique structure provides opportunities for studying the effects of bromine and formyl groups on reaction mechanisms and product outcomes.

Upstream product

• 14062-25-0 Ethyl 4-bromophenylacetate 
• 109-94-4 formic acid ethyl ester 
• 623-73-4 diazoacetic acid ethyl ester 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 104309-66-2 3-(p-bromophenyl)-6-methyl-2-pyrone 
• 91670-46-1 4-(4-Bromo-phenyl)-2H-isoxazol-5-one 
• 91632-35-8 4,4'-Bis-(4-bromo-phenyl)-4'H-[2,4']biisoxazolyl-5,5'-dione 
• 91632-59-6 (Z)-2-(4-Bromo-phenyl)-3-{[1-(4-bromo-phenyl)-1-cyano-meth-(Z)-ylidene]-amino}-acrylic acid methyl ester 
• 91632-54-1 (Z)-2-(4-Bromo-phenyl)-3-{[1-(4-bromo-phenyl)-1-cyano-meth-(Z)-ylidene]-amino}-acrylic acid 
• 91632-48-3 (Z)-3-(4-Bromo-benzoylamino)-2-(4-bromo-phenyl)-acrylic acid 
• 91632-41-6 2,5-Bis-(4-bromo-phenyl)-[1,3]oxazin-6-one 
• 1352442-41-1 3-(4-bromophenyl)-5,7-dimethoxyquinolin-4(1H)-one 
• 104309-68-4 4-(6-Methyl-2-oxo-2H-pyran-3-yl)-benzonitrile 
• 104920-86-7 8-acetamido-4-(4-bromophenyl)tetrazolo<1,5-a><1,8>naphthyridine 
• 104920-83-4 7-acetamido-3-(4-bromophenyl)-2-hydroxy-1,8-naphthyridine 
• 104949-90-8 7-acetamido-2-chloro-3-(4-bromophenyl)-1,8-naphthyridine 
• 104920-92-5 8-hydroxy-4-(4-bromophenyl)tetrazolo<1,5-a><1,8>naphthyridine 
• 104920-89-0 8-amino-4-(4-bromophenyl)tetrazolo<1,5-a><1,8>naphthyridine 

Relevant academic research and scientific papers

Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones

A series of 3-aryl-5,7-dimethoxyquinolin-4-ones 8 and 3-aryl-5,7-dimethoxy- 2,3-dihydroquinolin-4-ones 13 were synthesized in good yields. Demethylation under a range of conditions afforded the corresponding 5-hydroxy and 5,7-dihydroxy derivatives. Biolog

Lewis base catalyzed asymmetric hydrosilylation of α-substituted β-enamino esters: Facile access to enantioenriched β2-amino esters via dynamic kinetic resolution

A chiral Lewis base organocatalyzed asymmetric hydrosilylation of α-substituted β-enamino esters is presented. The reactions proceeded through dynamic kinetic resolution to afford various enantioenriched β2-amino esters with high yields (up to

Synthesis and in vitro evaluation of 3H-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activity

A series of new substituted 7-phenyl-3H-pyrrolo[3,2-f]quinolin-9-ones were synthesized and evaluated for their antiproliferative activity. The most active derivatives showed high selectivity against human leukemia cell lines and potently inhibited their g

Unusual anion effects in the iron-catalyzed formation of 3-hydroxyacrylates from aromatic aldehydes and ethyl diazoacetate

Due to the lability of one of the CO ligands in irans-[Fe(PNP)(CO) 2Cl]+ this compound is an efficient catalyst for the coupling of a series of aromatic aldehydes with ethyl diazoacetate (EDA), which give, in most cases, selectively 3-hydroxyacrylates rather than β-oxo esters. This reaction is strongly dependent on the nature of the counterion, Whereas with BF4- the reaction proceeds with conversions up to 90%, in the case of the counterions NO3-, CF 3COO-, CF3SO3-, SbF 6-, and BAr'4- [Ar' = 3,5-(CF 3)2C6H3] no reaction took place. In the case of PF6- only up to 20% conversion was achieved. A conceivable mechanism for the coupling of aromatic aldehydes with EDA was established by means of DFT/B3LYP calculations, which allowed the rationalization of both the chemoselectivity and the role of the counterions.

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials

A series of potential antimicrobial derivatives possessing bioisosteric replacements for the central oxazolidinone ring found in oxazolidinone antibacterials have been prepared. The design concept involved replacement of the requisite sp3-hybridized stereogenic center found at the 5-position of the oxazolidinone with a nitrogen atom. The synthesis and antibacterial activity of three such ring systems, the benzisoxazolinones, pyrroles, and isoxazolinones is described.