916326-10-8

Basic information

• Product Name: 3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER
• Synonyms: NICOTINIC ACID ETHYL ESTER-5-BORONIC ACID PINACOL ESTER;ETHYL NICOTINATE-5-PINACOLBORONATE;5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-NICOTINIC ACID ETHYL ESTER;3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER;5-(Ethoxycarbonyl)pyridine-3-boronic acid pinacol ester;5-(4,4,5,5-Teteramethyl-[1,3,2]dioxaboroane-2-yl)-nicotinic acid ethyl ester;5-(Ethoxycarbonyl)pyridine-3-bor;Nictinic acid ethyl ester-5-boronic acid pinacol ester
• CAS NO: 916326-10-8
• Molecular Formula: C₁₄H₂₀BNO₄
• Molecular Weight: 277.12
• Product Categories: Organoborons;Pyridine
• Mol File: 916326-10-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER(916326-10-8)
• EPA Substance Registry System: 3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER(916326-10-8)

Safety Data

• Hazardous Substances Data: 916326-10-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to form stable complexes with organic molecules, aiding in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER is utilized as a building block in the creation of crop protection products, leveraging its complex-forming properties to enhance the effectiveness of these products.
Used in Organic Synthesis:
3-(ETHOXYCARBONYL)PYRIDINE-5-BORONIC ACID PINACOL ESTER is employed as a versatile reagent in organic synthesis for its stability and solubility, making it easier to handle and manipulate in the synthesis of complex organic molecules.

InChI:InChI=1S/C14H20BNO4/c1-6-18-12(17)10-7-11(9-16-8-10)15-19-13(2,3)14(4,5)20-15/h7-9H,6H2,1-5H3

Upstream product

• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 20986-40-7 ethyl 5-bromo-3-pyridinecarboxylate 

Downstream Products

• 1031432-52-6 ethyl 6'-{[(ethylamino)carbonyl]amino}-4'-(4-phenyl-1,3-thiazol-2-yl)-3,3'-bipyridine-5-carboxylate 
• 1220418-63-2 ethyl 5-{2-[(3-chloro-4-fluorophenyl)amino]-4-(methylsulfonyl)pyrimidin-5-yl}pyridine-3-carboxylate 

Relevant articles and documents

Synthesis of ethyl nicotinate-5-boronic acid pinacol ester and its application toward Suzuki coupling

A method for the synthesis and isolation of pure ethyl nicotinate-5-boronic acid pinacol ester has been described. This boronate ester was used to prepare C2-C5 heteroarylnicotinates in good yields. Copyright Taylor & Francis Group, LLC.

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