91638-89-0Relevant academic research and scientific papers
Copper-catalyzed aerobic oxidative cross-coupling of arylamines and dialkylphosphites leading to N-arylphosphoramidates
Wang, Gao,Yu, Qing-Ying,Chen, Shan-Yong,Yu, Xiao-Qi
, p. 6230 - 6232 (2013)
An efficient method to generate N-P bonds directly from N-H and P-H bonds is described. Various arylamines and dialkylphosphites were directly oxidized to the corresponding N-arylphosphoramidates at room temperature in moderate to good yields by using an inexpensive catalyst-oxidant (CuBr/air) system.
Optimization of Phosphoramidates Synthetic Conditions
Khan,Khan
, p. 564 - 565 (2018/04/23)
An optimized catalytic oxidative cost effective process of dehydrogenative coupling of diisopropyl phosphite with arylamines led to formation of the corresponding phosphoramidates. Structures of products were elucidated from NMR and ESI-MS data.
Kinetics and mechanism of the anilinolysis of diisopropyl chlorophosphate in acetonitrile
Ul Hoque, Md. Ehtesham,Lee, Hai Whang
experimental part, p. 3245 - 3250 (2012/01/17)
The nucleophilic substitution reactions of diisopropyl chlorophosphate (3) with substituted anilines (XC6H4NH2) and deuterated anilines (XC6H4ND2) are investigated kinetically in acetonitrile at 55.0 oC. The anilinolysis rate of 3 is rather slow to be rationalized by the conventional stereoelectronic effects. The obtained deuterium kinetic isotope effects (DKIEs; kH/kD) are secondary inverse (kH/kD = 0.71-0.95) with maximum magnitude at X = H. A concerted mechanism involving predominant backside nucleophilic attack is proposed on the basis of the secondary inverse DKIEs.
