91652-58-3

Upstream product

• 96624-91-8 N-<4-butyl>toluol-4-sulfonamid 
• 4748-73-6 N-(cyanoethyl)-1,4-diaminobutane 

Downstream Products

• 91652-59-4 C₃₇H₅₈N₄O₇S₂ 
• 91653-21-3 13-Nitro-N-<4-tosyl-8-(tosylamino)-4-azaoctyl>-16-hexadecanlactam 
• 467457-28-9 (+)-(3S)-4-hydroxy-3-{[(4-methylphenyl)sulfonyl]amino}-N-{3-[[(4-methylphenyl)sulfonyl](4-{[(4-methylphenyl)sulfonyl]amino}butyl)amino]propyl}butanamide 
• 467457-36-9 (+)-(3R)-3-{[(4-methylphenyl)sulfonyl]amino}-N-{3-[[(4-methylphenyl)sulfonyl](4-{[(4-methylphenyl)sulfonyl]amino}butyl)amino]propyl}tetradecanamide 
• 91652-54-9 N-<4-Tosyl-8-(tosylamino)-4-azaoctyl>-16-hexadecanlactam 
• 91652-53-8 13-Oxo-N-<4-tosyl-8-(tosylamino)-4-azaoctyl>-16-hexadecanlactam 
• 91652-55-0 13,13-(Aethylendithio)-N-<4-tosyl-8-(tosylamino)-4-azaoctyl>-16-hexadecanlactam 

Relevant academic research and scientific papers

(-)-(3S)-3-(Tosylamino)butano-4-lactone, a versatile chiral synthon for the enantioselective synthesis of different types of polyamine macrocycles: Determination of the absolute configuration of (-)-(R)-budmunchiamine A

(-)-(3S)-3-(Tosylamino)butano-4-lactone (1) and its derivative ethyl (-)-(3S)-4-iodo-3-(tosylamino)butanoate (2) are presented as easily accessible chiral building blocks for the construction of a range of different macrolactam frameworks important for th

Synthetic Analogues of Low-Molecular-Weight Acyl-polyamine Spider Toxins

Low-molecular-weight spider and wasp toxins are selective inhibitors of glutamate receptors of the central nervous system and consist of a polyamine backbone and one or several carboxylic acids and/or amino acids linked by a peptide-like bond.The syntheses of twelve analogues of spider and wasp toxins are described (10a-c, 15a-c, 20a-c, 25a-c) having the general structure of acyl, arylacyl, or heteroarylacyl -> DL-alanyl -> ω-aminoacyl -> N1-spermidine, with variation in the acyl and the ω-aminoacyl part.

RING EXPANSION REACTIONS IN THE FORMATION OF MACROCYCLIC LACTAMS. A SYNTHESIS OF DESOXO-INANDENINE

Desoxo-inandenine, a reduction product of the macrocyclic spermidine alkaloids inandenin-12-one and -13-one has been synthesized from 2-nitro-cyclotridecanone by ring expansion reactions including a Zip reaction step.

Synthese von N-(4-Aminobutyl)-16-aza-19-nonadecanlactam und N-(4-Aminobutyl)-17-aza-20-icosanlactam (Desoxoinandenin)

According to Scheme 1, the two homologous macrocyclic spermidine derivatives 12 ad 23 were synthesized.Key steps in both cases were two different types of ring-enlargement reactions.Compound 12 was identical with a degradation product of the naturally occurring spermidine akaloids of inandine-type.