91657-16-8Relevant academic research and scientific papers
INTRAMOLECULAR CARBOMETALLATION OF GRIGNARD REAGENTS HAVING THE TERMINAL TRIMETHYLSILYLACETYLENE GROUP
Fujikura, Sadao,Inoue, Masaharu,Utimoto, Kiitiro,Nozaki, Hitosi
, p. 1999 - 2002 (2007/10/02)
Reaction of 6-bromo-1-trimethylsilyl-1-hexyne with magnesium affords the corresponding Grignard reagent whose C-Mg bond intramolecularly adds to the trimethylsilylacetylene moiety in 5-Exo-Dig manner and suprafacially.The reaction can be applied to the synthesis of some cycloalkanes having stereodefined alkylidene substituents.
