916571-99-8

Basic information

• Product Name: 5-fluorobenzo[d]isoxazol-3-amine
• Synonyms: 5-fluorobenzo[d]isoxazol-3-amine ;5-Fluorobenzo[d]isoxazol-3-aMine hydrochloride
• CAS NO: 916571-99-8
• Molecular Formula: C7H6ClFN2O
• Molecular Weight: 188.5867432
• Mol File: 916571-99-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-fluorobenzo[d]isoxazol-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluorobenzo[d]isoxazol-3-amine(916571-99-8)
• EPA Substance Registry System: 5-fluorobenzo[d]isoxazol-3-amine(916571-99-8)

Safety Data

• Hazardous Substances Data: 916571-99-8(Hazardous Substances Data)

Usage

Description

5-fluorobenzo[d]isoxazol-3-amine is a heterocyclic chemical compound characterized by a molecular formula of C7H5FN2O and a molecular weight of 146.13 g/mol. It is a derivative of benzo[d]isoxazole, featuring a benzene ring fused to an isoxazole ring with a fluorine atom at the 5-position and an amine group at the 3-position. 5-fluorobenzo[d]isoxazol-3-amine holds potential in pharmaceutical and medicinal chemistry due to its structural resemblance to other biologically active molecules, suggesting possible biological activity that warrants further exploration in laboratory studies and clinical research.

Uses

Used in Pharmaceutical Industry:
5-fluorobenzo[d]isoxazol-3-amine is used as a potential pharmaceutical intermediate for the synthesis of various drug candidates. Its unique structure allows for the development of new compounds with potential therapeutic properties, including but not limited to, analgesics, anti-inflammatory agents, and antimicrobials.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-fluorobenzo[d]isoxazol-3-amine serves as a key building block for the design and synthesis of novel bioactive molecules. Its presence in compound libraries can facilitate the discovery of new lead compounds with improved pharmacological profiles, such as enhanced potency, selectivity, and reduced side effects.
Used in Drug Discovery:
5-fluorobenzo[d]isoxazol-3-amine is utilized in drug discovery processes as a structural motif that can be incorporated into diverse chemical scaffolds. Its incorporation may enhance the binding affinity, selectivity, and overall drug-like properties of newly synthesized compounds, thereby increasing their chances of progressing through the drug development pipeline.
Used in Chemical Synthesis:
As a versatile chemical intermediate, 5-fluorobenzo[d]isoxazol-3-amine is employed in the synthesis of a wide range of organic compounds, including agrochemicals, dyes, and materials with specific properties. Its reactivity and functional groups enable various synthetic transformations, broadening its applicability in the chemical industry.
Used in Biochemical Research:
5-fluorobenzo[d]isoxazol-3-amine may also find use in biochemical research as a tool compound to probe the structure-activity relationships of biologically active molecules. Its introduction into biological assays can provide insights into the molecular mechanisms of action and help elucidate the binding interactions with target proteins or enzymes.

Relevant articles and documents

SUBSTITUTED N-BENZO [D] ISOXAZOL-3-YL-AMINE DERIVATIVES AS INHIBITORS OF MGLUR5, SEROTONINE (5-HT) AND NORADRENALINE RECEPTORS, AND THE USE THEREOF FOR PRODUCING MEDICAMENTS

The invention relates to substituted N-benzo[d]isoxazol-3-yl-amine derivatives of formula (I) wherein R1,R2,R3,R4 and R5 are defined as in patent claim 1. The invention also relates to the use of said compounds for producing medicaments.