916666-95-0

Basic information

• Product Name: 4-(4-Isopropoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(4-Isopropoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 916666-95-0
• Molecular Weight: 363.457
• Mol File: 916666-95-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-Isopropoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Isopropoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester(916666-95-0)
• EPA Substance Registry System: 4-(4-Isopropoxy-phenylcarbamoyl)-piperazine-1-carboxylic acid tert-butyl ester(916666-95-0)

Safety Data

• Hazardous Substances Data: 916666-95-0(Hazardous Substances Data)

Upstream product

• 916610-30-5 (4-isopropoxy-phenyl)-carbamic acid 4-nitro-phenyl ester 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 7664-66-6 4-(isopropoxy)aniline 

Downstream Products

• 792899-38-8 N-(4-isopropoxyphenyl)piperazine-1-carboxamide 

Relevant articles and documents

AMINOPYRIMIDINES AS KINASE MODULATORS

Abstract The invention is directed to aminopyrimidine compounds of Formula I: where R3, B, Z, r and R1 are as defined herein, the use of such compounds as protein tyrosine kinase modulators, particularly inhibitors of FLT3 and/or c-kit and/or TrkB, the use of such compounds to reduce or inhibit kinase activity of FLT3 and/or c-kit and/or TrkB in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to FLT3 and/or c-kit and/or TrkB . The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as cancers and other cell proliferative disorders.