91676-48-1Relevant academic research and scientific papers
Evaluation of novel synthetic methods for the preparation of the sodium channel inhibitor, GW273225X
Walker, Matthew D.,Albinson, F. David,Clark, Hugh F.,Clark, Stacy,Henley, Nicholas P.,J. Horan, Richard A.,Jones, Chris W.,Wade, Charles E.,Ward, Richard A.
, p. 82 - 88 (2014/05/20)
The evaluation of efficient synthetic methods for the preparation of (R)-2,4-diamino-5-(2,3-dichlorophenyl)-6- fluoromethylpyrimidine, GW273225X (1), is described. The initial synthesis using ethylfluoroacetate was evaluated against three alternative rout
