Cas 916793-74-3,(2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

916793-74-3

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Basic information

Product Name: (2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
Synonyms: (2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
CAS NO:916793-74-3
Molecular Formula:
Molecular Weight: 535.722
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
NIST Chemistry Reference: (2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester(916793-74-3)
EPA Substance Registry System: (2R,3S,5S)-5-((2S,4S)-5-hydroxy-4-isopropyl-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester(916793-74-3)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
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RTECS:
HazardClass: N/A
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Hazardous Substances Data: 916793-74-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 916793-74-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,7,9 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 916793-74:
(8*9)+(7*1)+(6*6)+(5*7)+(4*9)+(3*3)+(2*7)+(1*4)=213
213 % 10 = 3
So 916793-74-3 is a valid CAS Registry Number.

916793-74-3Upstream product

916793-73-2 (2R,3S,5S)-5-((1S,3S)-1-hydroxymethyl-3-hydroxymethyl-4-methyl-pentyl)-3-isopropyl-2-[4-methoxy-3-(3-methoxy-propoxy)-phenyl]pyrrolidine-1-carboxylic acid tert-butyl ester

916793-74-3Downstream Products

916793-75-4 (2R,3S,5S)-3-isopropyl-5-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-isopropyl-2-[4-methoxy-3-(3-methoxypropoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester

916793-74-3Relevant academic research and scientific papers

SYTHESIS OF RENIN INHIBITORS INVOLVING A CYCLOADDITION REACTION

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Page/Page column 56, (2010/11/26)

The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula (III), wherein R, R1, and R' are as defined in the specification, or a salt thereof, and a compound of formula (IV) wherein R, R1, R2 and R' are as defined in the specification, and processes of manufacturing these.

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