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[R,(-)]-3,4,5,6,7,8-Hexahydro-2-oxo-4aβ(2H)-naphthalenecarboxylic acid, also known as (–)-Dihydrokavain, is a naturally occurring kavalactone derived from the kava plant. It is a chemical compound that belongs to the class of carboxylic acids and has been studied for its potential pharmacological effects.

91684-28-5

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91684-28-5 Usage

Uses

Used in Pharmaceutical Industry:
[R,(-)]-3,4,5,6,7,8-Hexahydro-2-oxo-4aβ(2H)-naphthalenecarboxylic acid is used as a muscle relaxant for its potential to alleviate muscle tension and spasms, providing relief to patients suffering from various muscle-related conditions.
Used in Neuropsychopharmacology:
[R,(-)]-3,4,5,6,7,8-Hexahydro-2-oxo-4aβ(2H)-naphthalenecarboxylic acid is used as an anxiolytic agent for its potential to reduce anxiety and stress without causing the negative side effects often associated with traditional anxiolytics.
Used in Neurological Disorder Treatment:
[R,(-)]-3,4,5,6,7,8-Hexahydro-2-oxo-4aβ(2H)-naphthalenecarboxylic acid is used as a potential treatment for certain neurological disorders due to its pharmacological effects, which may help in managing the symptoms and improving the quality of life for patients with these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 91684-28-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,6,8 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 91684-28:
(7*9)+(6*1)+(5*6)+(4*8)+(3*4)+(2*2)+(1*8)=155
155 % 10 = 5
So 91684-28-5 is a valid CAS Registry Number.

91684-28-5Upstream product

91684-28-5Relevant academic research and scientific papers

Enantioselectivity of Microbial Hydrolysis of (+/-)-Decahydro-2-naphthyl Acetates. Preparation and Absolute Configurations of Chiral Decahydro-2-naphthols

Oritani, Takayuki,Yamashita, Kyohei,Kabuto, Chizuko

, p. 3689 - 3694 (2007/10/02)

Absolute configurations of chiral decahydro-2-naphthols, which were obtained by microbial hydrolysis of corresponding (+/-)-acetates and chloroacetates, were elucidated by chemical correlation to (4aS,8aS)-trans-octahydro-2(1H)-naphthalenone (5).Decarboxylation of the (-)-α-methylbenzylamine salt of (-)-2-oxo-2,3,4,4a,5,6,7,8-octahydro-4a-naphthalenecarboxylic acid (1a) gave (+)-(S)-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone (3), which was reduced with lithium in liquid ammonia to (+)-(4aS,8aS)-trans-octahydro-2(1H)-naphthalenone (5).Catalytic hydrogenation of (-)-3gave (-)-(4aR,8aS)-cis-octahydro-2(1H)-naphthalenone (4), which was already obtained by oxidation of (-)-cis,cis-decahydro-2-naphthol (7) with chromic acid.These results mean that (-)-7 has the 2S,4aR,8aS configuration.Furthermore, the absolute configuration of (-)-7 was confirmed by X-ray analysis of its p-bromobenzoate.

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