916885-85-3Relevant academic research and scientific papers
Azabicyclic amino acids by stereoselective dearomatizing cyclization of the enolates of N-nicotinoyl glycine derivatives
Arnott, Gareth,Clayden, Jonathan,Hamilton, Stuart D.
, p. 5325 - 5328 (2007/10/03)
On activation by pyridine N-acylation, enolates of N-nicotinoyl and N-isonicotinoyl glycine and alanine derivatives cyclize to yield 6,5-azabicyclic or 6,4-azaspirocyclic lactams. With an N-α-methyl-p-methoxybenzyl group the cyclization is diastereoselect
