917029-16-4

Upstream product

• 771-15-3 2-bromo-1-naphthol 
• 917029-12-0 (R(P))-(1-hydroxy-2-naphthyl)(methyl)(phenyl)phosphine-P-borane 
• 917029-07-3 methyl (S(P))-(1-hydroxy-2-naphthyl)(phenyl)phosphinite-P-borane 

Downstream Products

• 917029-56-2 (R(P),R(P))-1,2-bis[(1-methoxy-2-naphthyl)(phenyl)phosphino-P-borane]ethane 

Relevant academic research and scientific papers

Asymmetric synthesis of SMS-Phos series' precursor and a naphthalene analogue

An efficient and high-yielding (up to 57% overall yield) asymmetric route to enantiopure P-stereogenic 1,2-bis[(o-hydroxyaryl)(phenyl)phosphino-P-borane] ethanes wherein aryl = phenyl and naphthyl, is presented. The occurring P-stereomutation is confirmed

NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS

The invention relates to novel organo phosphorus P-chiral optically active compounds of formula (I) having a hydroxyl, mercapto, amino, carboxyl, sulfonyl group on aryl near a phosphorus atom, to the preparation and the use thereof in then asymmetrical catalysis of unsaturated compounds. Novel acylphosphine optically pure ligands embodied in the form of transition metal complexes exhibit an increased activity and enantloselectivity, in particular in asymmetrical hydrogenation, in comparison with the same type Uganda such as DiPAMP.